Although salvage prostate bed radiotherapy is highly effective in biochemically-relapsing prostate cancer patients following prostatectomy, relapses remain frequent and improvements are needed.Randomized phase 3 trials have shown the benefit of adding androgen-depriving therapy to irradiation, but not all patients benefit from this combination.Prec
Understanding the pathogenesis of different phenotypes of asthma, including glucocorticoid-dependent and glucocorticoid-resistant asthma, is crucial for the development of effective treatments.Autophagy, a fundamental cellular process involved in cell homeostasis, has afck benchmade been implicated in asthma, although the exact mechanisms remain un
Background.Hyperglycemia is common and difficult to control in perioperative patients with type 2 diabetes mellitus (T2DM), which impacts their prognosis after operation.Our study investigated the short-term effect of continuous subcutaneous insulin infusion (CSII) and multiple 730 sunken lake road daily injection (MDI) in perioperative T2DM patien
Coxiella burnetii is the etiological agent of the zoonotic disease Q fever, which is featured by its ability to replicate in acid vacuoles resembling the lysosomal network.One key virulence determinant of C.burnetii is the Dot/Icm system that transfers more than 150 effector proteins into host cells.These effectors function to construct the lysosom